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Erin McCarthy

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Erin McCarthy

Erin McCarthy

Erin McCarthy is originally from Erie, PA. She attended Mercyhurst University and graduated in 2013 with a B.S. in Biochemistry. Following her graduation, she was employed at Hero BX in Erie, PA where her work focused on the production of biodiesel on an industrial scale. She came to Penn State in the Fall of 2014 to join the Biochemistry, Microbiology, and Molecular Biology (BMMB) program, and joined the lab of Howard Hughes Investigator Squire J. Booker in February 2015. Since that time, her work has centered on understanding the mechanism by which radical SAM enzymes that destroy their iron-sulfur cluster cofactors during catalysis get regenerated for subsequent turnover. In particular, the focus of her research has been lipoyl synthase which sacrifices its auxiliary cluster to use as a sulfur source in the biosynthesis of lipoic acid. Her research seeks to expand our understanding of a variety of poorly understood molecular processes, including sulfur appendage to unactivated carbon centers and Fe–S cluster assembly and delivery.