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Siobhán MacArdle

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Siobhán MacArdle

Siobhan MacArdle

Siobhán MacArdle was born in Berkeley, California and graduated from Berkeley High School in 2010. She then moved to NewYork to attend Barnard College where she received a B.A. in Biochemistry. During her undergraduate education, Siobhán worked in Professor Marisa Buzzeo’s lab at Barnard College toward the development of an electrochemical sensor for microRNA. This research sparked Siobhán’s interest in the field of bioelectrochemistry and she wanted to continue studying biological systems using electrochemical techniques. While at Barnard, Siobhán worked as a teaching assistant in the organic chemistry laboratory and as a bottler and distilling intern at Kings County Whiskey Distillery in Brooklyn. After graduating from Barnard College in 2014, she moved to Dublin, Ireland to work for Professor Dermot Diamond at the National Centre for Sensor Research at Dublin City University. Here, her research involved synthesizing and characterizing pH- and light-responsive hydrogels for use in electrochemical sensors.


Siobhán began her graduate education in the Chemistry and Chemical Engineering Division at Caltech in 2015 and joined Professor Jackie Barton’s lab. The focus of her work is the electrochemical characterization of the 4Fe-4S cluster of S. cerevisiae Dna2. Siobhán’s work ranges from the biochemistry of overexpression and purification of S. cerevisae Dna2 in E. coli to the DNA-modified electrochemistry pioneered by the Barton lab. She also synthesizes the multiplexed gold electrodes used by the group in the Kavli Nanoscience Institute at Caltech.



Siobhán has been a member of the Caltech Women in Chemistry Committee for the last two years.