You are here: Home Speakers Radical S-adenosyl-L-methionine (SAM) Session

Radical S-adenosyl-L-methionine (SAM) Session

Main Content

Vahe Bandarian

Main Content

Vahe Bandarian

Professor
University of Utah

 Vahe Bandarian

Vahe Bandarian (b. 1970) received his BS degree in Biochemistry from the California State University in Los Angeles in 1992.  He received his PhD in Biochemistry in 1998 from the University of Wisconsin-Madison working under the direction of George Reed.  After carrying out postdoctoral studies with Rowena Matthews at the University of Michigan in Ann Arbor he joined the faculty of the Department of Biochemistry at the University of Arizona in 2003.  In 2015 he moved as Professor of Chemistry to the University of Utah.  Vahe’s lab studies biosynthetic pathways to natural products that include modified nucleic acids and peptides.  His contributions have been recognized by a Burroughs Wellcome Career Award in Biomedical Sciences and the Pfizer Award in Enzyme Chemistry by the Division of Biological Chemistry at ACS. 

 

Learn more about Dr. Bandarian here.
 
Learn more about the Bandarian Research Group here.

Mohammed Seyedsayamdost

Main Content

Mohammed Seyedsayamdost

Assisant Professor of Chemistry & Molecular Biology
Princeton University

Mohammed Seyedsayamdost

Mo was born in Iran and grew up in Germany and Australia before entering Brandeis University (Waltham, MA) for his undergraduate studies. There he obtained a 4-year combined B.S./M.S. degree in Biochemistry with highest honors. His undergraduate thesis was carried out in the laboratory of Prof. Lizbeth Hedstrom on the chemical mechanism of inosine-5′-monophosphate dehydrogenase, an important target of immunosuppressive drugs. Mo carried out his graduate studies in the Department of Chemistry at MIT under the guidance of Prof. JoAnne Stubbe. His PhD thesis combined methods for site-specific incorporation of unnatural amino acids with rapid kinetic and spectroscopic techniques in order to examine the mechanism of ribonucleotide reductase, an essential metalloenzyme in all living cells. These studies revealed an unprecedented pathway and mechanism for long-range proton-coupled electron transfer catalyzed by transient amino acid radicals. He then joined the labs of Prof. Jon Clardy and Prof. Roberto Kolter as a Novartis LSRF postdoctoral fellow at Harvard Medical School, where he examined the roles of small molecules in mediating microbial interspecies interactions. This work led to the discovery of a novel family of phytotoxins as well as to new approaches for prospecting for bioactive small molecules. In January 2013, Mo started as an assistant professor in the Department of Chemistry at Princeton University. His lab is interested in the discovery, structure, function, and biosynthesis of new small molecules with bioactive or therapeutic properties. These studies blend approaches from microbiology, bacterial genetics, small molecule chemistry, biochemistry, and mechanistic enzymology.

 

Mo has been the recipient of the Novartis Life Sciences Research Foundation Fellowship, the NIH Pathway to Independence Award (K99/R00), the Searle Scholars Award, the Pew Biomedical Scholars Awards, co-recipient of the Princeton Environmental Institute’s Innovative Research Award, and the NIH Director’s New Innovator Award.

 

Learn more about The Seyedsayamdost Research Group here.

Kenichi Yokoyama

Main Content

Kenichi Yokoyama

Assistant Professor of Biochemistry
Duke University Medical Center

 Kenichi Yokoyama

Dr. Yokoyama’s group has been studying biosynthesis and mechanism of actions of medicinally important cofactors and natural products. One of our focus is C-C bond forming radical SAM enzymes critical for the formation of the carbon skeletons of the metabolites. Our studies are revealing the mechanisms of enzymes, in which highly reactive free radicals are used to construct structurally complex metabolites.

Learn more about the Yokoyama Lab here.

Document Actions